Pharmaceutical plant

Daikin's HFO screw inverter chiller technology solution for a major pharmaceutical company manufacturing site in Wien Austria.
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Daikin has supplied HFO screw inverter chiller technology to a major pharmaceutical company, for one of the manufacturing sites in Wien, Austria.

The Daikin screw inverter chillers replaced old high GWP chiller units.



Total cooling capacity: 580 kW


The project required the replacement of a 15 years old big split chiller R410A with remote air-cooled condensers. The refrigerant quantity in the old chiller was very high and the reciprocating compressor only had 4 capacity steps. The end user decided to replace it with more advanced technology, seeking greater energy efficiency and environmentally friendliness.

The new chillers had to produce chilled water/glycol mixture at -8°C, which to provide cooling for microbiological processes.

During the investigation for replacement the end user made several measurements in “real life” operations and found out that the cooling requirement could vary from approximately from 70 kW to 570 kW.

Another important aspect was the noise reduction. The project required a maximum sound power of 81 dBA.


The main aspect driving the consultants’ choice towards Daikin’s screw inverter solutions were the ability to offer the great reliability of the in-house developed screw compressor paired up with HFO refrigerant, fully meeting the needs of the facility involved.

The project required an environmentally friendly HVAC concept. That is why it was decided to use chillers featuring R-1234ze. This refrigerant sets the new standard for environmentally friendly cooling systems. In fact, with a GWP (Global Warming Potential) 200 times lower than R-134A, it is a much greener option, and paired up with Daikin’s Single Screw compressors technology can ensure outstanding energy efficiency levels.

The low noise requirement, then, was addressed thanks an optimization of the reduced sound configuration in the TZ Series.